Antigenic screening method for genetic studies
نویسندگان
چکیده
منابع مشابه
Phenylketonuria screening registry as a resource for population genetic studies.
BACKGROUND Neonatal screening for metabolic diseases, involving samples stored on filter paper (Guthrie spots), provides a potential resource for genetic epidemiological studies. OBJECTIVE To develop a method to make these dried blood spots available for large scale genetic epidemiology. METHODS DNA from untraceable Guthrie spots was extracted using a saponin and chelex-100 based method and...
متن کاملStudies on Antigenic Competition
Antigenic competition was studied in a haptenic system. It was found that: (a) The extent of competition is greater when larger doses of antigen are employed. (b) Antigenic competition appears to be independent of the carrier molecule. (c) The affinity of the antibody produced in antigenic competition is approximately equal to the affinity of antibody formed by animals immunized with only one a...
متن کاملFurther Studies of Antigenic Competition
A striking correlation between the capacity of an antigen to nonspecifically suppress humoral immune responses of subsequently administered antigens which are non-cross-reacting, i.e. to manifest antigenic competition and produce enlargement of spleen size through cell proliferation, was found. Increase in spleen size was always accompanied by a drop in the normal proportion of thymus-derived c...
متن کاملQuantitative Studies on Antigenic Recognition
Lymphoid cells from normal animals from two genetically alien but isogenic strains of mice or rats elaborated a factor into the medium during in vitro cultivation. Similarly, lymphoid cells from specifically presensitized animals mixed and cultivated with donor-type lymphoid cells, as well as normal or specifically immunized mouse spleen cells exposed to heterologous red blood cell antigens, fo...
متن کاملScreening for Chlamydia trachomatis among Infertile Women Using PCR Method
Background & objectives: Chlamydia trachomatis is a gram negative bacterium and chlamydia infection, as a curable infection, is one of the most common sexually transmitted diseases (STD). With regard to the essential role of chlamydia in infertility, the study of the prevalence of asymptomatic cases is precious. The aim of this study was to determine of the prevalence of chlamydia trachomatis...
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ژورنال
عنوان ژورنال: Fungal Genetics Reports
سال: 1972
ISSN: 1941-4765
DOI: 10.4148/1941-4765.1869